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Muscone/RI7217 co-modified upward messenger DTX liposomes enhanced permeability of blood-brain barrier and targeting glioma

Rationale: The dual-targeted drug delivery system was designed for enhancing permeation of the blood-brain barrier (BBB) and providing an anti-glioma effect. As transferrin receptor (TfR) is over-expressed by the brain capillary endothelial (hCMEC/D3) and glioma cells, a mouse monoclonal antibody, R...

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Detalles Bibliográficos
Autores principales: Kang, Shuangming, Duan, Wenjuan, Zhang, Shangqian, Chen, Dawei, Feng, Jianfang, Qi, Na
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7150489/
https://www.ncbi.nlm.nih.gov/pubmed/32292496
http://dx.doi.org/10.7150/thno.41322