Cariogenic Streptococcus mutans Produces Tetramic Acid Strain-Specific Antibiotics That Impair Commensal Colonization

[Image: see text] Streptococcus mutans is a common constituent of dental plaque and a major etiologic agent of dental caries (tooth decay). In this study, we elucidated the biosynthetic pathway encoded by muc, a hybrid polyketide synthase and nonribosomal peptide synthetase (PKS/NRPS) biosynthetic g...

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Detalles Bibliográficos
Autores principales: Tang, Xiaoyu, Kudo, Yuta, Baker, Jonathon L., LaBonte, Sandra, Jordan, Peter A., McKinnie, Shaun M. K., Guo, Jian, Huan, Tao, Moore, Bradley S., Edlund, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7150634/
https://www.ncbi.nlm.nih.gov/pubmed/31906623
http://dx.doi.org/10.1021/acsinfecdis.9b00365

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7150634/
https://www.ncbi.nlm.nih.gov/pubmed/31906623
http://dx.doi.org/10.1021/acsinfecdis.9b00365

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