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Structural and Functional Characterization of the Bestrophin-2 Anion Channel
The bestrophin family of calcium (Ca(2+))-activated chloride (Cl(−)) channels, which mediate the influx and efflux of monovalent anions in response to the levels of intracellular Ca(2+), comprises four members in mammals (Best1-4). Here we report cryo-EM structures of bovine Best2 (bBest2) bound and...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7150642/ https://www.ncbi.nlm.nih.gov/pubmed/32251414 http://dx.doi.org/10.1038/s41594-020-0402-z |