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Structural and Functional Characterization of the Bestrophin-2 Anion Channel

The bestrophin family of calcium (Ca(2+))-activated chloride (Cl(−)) channels, which mediate the influx and efflux of monovalent anions in response to the levels of intracellular Ca(2+), comprises four members in mammals (Best1-4). Here we report cryo-EM structures of bovine Best2 (bBest2) bound and...

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Detalles Bibliográficos
Autores principales:	Owji, Aaron P., Zhao, Qingqing, Ji, Changyi, Kittredge, Alec, Hopiavuori, Austin, Fu, Ziao, Ward, Nancy, Clarke, Oliver B., Shen, Yin, Zhang, Yu, Hendrickson, Wayne A., Yang, Tingting
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7150642/ https://www.ncbi.nlm.nih.gov/pubmed/32251414 http://dx.doi.org/10.1038/s41594-020-0402-z

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