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Murine Precision-cut Intestinal Slices as a Potential Screening Tool for Antifibrotic Drugs
BACKGROUND: Intestinal fibrosis is a hallmark of Crohn’s disease. Here, we investigated the impact of several putative antifibrotic compounds on the expression of fibrosis markers using murine precision-cut intestinal slices. METHODS: Murine precision-cut intestinal slices were cultured for 48 hours...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7150673/ https://www.ncbi.nlm.nih.gov/pubmed/31943022 http://dx.doi.org/10.1093/ibd/izz329 |