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Methylation Pattern of the SOCS3 and IL6R Promoters in Rheumatoid Arthritis

Interleukin-6 (IL-6) plays an essential function in the development of rheumatoid arthritis (RA), mainly through its proinflammatory effect, which may lead to joint destruction. The genes encoding IL-6 receptor (IL6R) and suppressor of cytokine signaling 3 (SOCS3) play a key role in the IL-6 signali...

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Detalles Bibliográficos
Autores principales: Cieśla, Marek, Kolarz, Bogdan, Majdan, Maria, Darmochwał-Kolarz, Dorota
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7150677/
https://www.ncbi.nlm.nih.gov/pubmed/32292581
http://dx.doi.org/10.1155/2020/8394659