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Methylation Pattern of the SOCS3 and IL6R Promoters in Rheumatoid Arthritis
Interleukin-6 (IL-6) plays an essential function in the development of rheumatoid arthritis (RA), mainly through its proinflammatory effect, which may lead to joint destruction. The genes encoding IL-6 receptor (IL6R) and suppressor of cytokine signaling 3 (SOCS3) play a key role in the IL-6 signali...
Autores principales: | Cieśla, Marek, Kolarz, Bogdan, Majdan, Maria, Darmochwał-Kolarz, Dorota |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7150677/ https://www.ncbi.nlm.nih.gov/pubmed/32292581 http://dx.doi.org/10.1155/2020/8394659 |
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