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Monocarboxylate Transporter 6-Mediated Interactions with Prostaglandin F(2α): In Vitro and In Vivo Evidence Utilizing a Knockout Mouse Model

Monocarboxylate transporter 6 (MCT6; SLC16A5) is a recently studied drug transporter that currently has no annotated endogenous function. Currently, only a handful of compounds have been characterized as substrates for MCT6 (e.g., bumetanide, nateglinide, probenecid, and prostaglandin F(2α) (PGF2α))...

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Detalles Bibliográficos
Autores principales: Jones, Robert S., Parker, Mark D., Morris, Marilyn E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7150767/
https://www.ncbi.nlm.nih.gov/pubmed/32110957
http://dx.doi.org/10.3390/pharmaceutics12030201