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Acquisition of Avian-Origin PB1 Facilitates Viral RNA Synthesis by the 2009 Pandemic H1N1 Virus Polymerase

The constant crosstalk between the large avian reservoir of influenza A viruses (IAV) and its mammalian hosts drives viral evolution and facilitates their host switching. Direct adaptation of an avian strain to human or reassortment between avian-origin gene segments with that of human strains are t...

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Detalles Bibliográficos
Autores principales: Wang, Fangzheng, Liu, Guanqun, Lu, Yao, Hlasny, Magda, Liu, Qiang, Zhou, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7150768/
https://www.ncbi.nlm.nih.gov/pubmed/32121117
http://dx.doi.org/10.3390/v12030266