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Baseline Amino Acid Substitutions in the NS5A ISDR and PKR Binding Domain of Hepatitis C and Different Fibrosis Levels and Levels of Development of Hepatocellular Carcinoma in Patients Treated with DAAs

Variations in the interferon sensitivity-determining region (ISDR) within the NS5A region were related to the development of hepatocellular carcinoma (HCC) in patients infected with hepatitis C virus (HCV). The aim of the study was to investigate a relationship between ISDR/PKR substitutions and the...

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Detalles Bibliográficos
Autores principales: Paolucci, Stefania, Piralla, Antonio, Novazzi, Federica, Fratini, Alice, Maserati, Renato, Gulminetti, Roberto, Novati, Stefano, Barbarini, Giorgio, Sacchi, Paolo, De Silvestri, Annalisa, Baldanti, Fausto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7150791/
https://www.ncbi.nlm.nih.gov/pubmed/32106574
http://dx.doi.org/10.3390/v12030255