A Quinolinone Compound Inhibiting the Oligomerization of Nucleoprotein of Influenza A Virus Prevents the Selection of Escape Mutants

The emergence of resistance to currently available anti-influenza drugs has heightened the need for antivirals with novel mechanisms of action. The influenza A virus (IAV) nucleoprotein (NP) is highly conserved and essential for the formation of viral ribonucleoprotein (vRNP), which serves as the te...

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Detalles Bibliográficos
Autores principales: Makau, Juliann Nzembi, Watanabe, Ken, Otaki, Hiroki, Mizuta, Satoshi, Ishikawa, Takeshi, Kamatari, Yuji O., Nishida, Noriyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7150793/
https://www.ncbi.nlm.nih.gov/pubmed/32204549
http://dx.doi.org/10.3390/v12030337

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7150793/
https://www.ncbi.nlm.nih.gov/pubmed/32204549
http://dx.doi.org/10.3390/v12030337

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