Ex Vivo Rat Transected Spinal Cord Slices as a Model to Assess Lentiviral Vector Delivery of Neurotrophin-3 and Short Hairpin RNA against NG2

The failure of the spinal cord to regenerate can be attributed both to a lack of trophic support for regenerating axons and to upregulation of inhibitory factors such as chondroitin sulphate proteoglycans including NG2 following injury. Lentiviral vector-mediated gene therapy is a possible strategy...

Descripción completa

Detalles Bibliográficos
Autores principales: Patar, Azim, Dockery, Peter, McMahon, Siobhan, Howard, Linda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7150802/
https://www.ncbi.nlm.nih.gov/pubmed/32183469
http://dx.doi.org/10.3390/biology9030054

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7150802/
https://www.ncbi.nlm.nih.gov/pubmed/32183469
http://dx.doi.org/10.3390/biology9030054

Ejemplares similares