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Method for Pulmonary Administration Using Negative Pressure Generated by Inspiration in Mice

When developing inhaled medicines for respiratory diseases, such as chronic obstructive pulmonary disease, drugs need to be administered by pulmonary delivery to animals in non-clinical tests. Common methods require application of pressure during administration, and it may cause lung injury, so we f...

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Detalles Bibliográficos
Autores principales: Oiso, Yuki, Akita, Tomomi, Kato, Daiki, Yamashita, Chikamasa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7150831/
https://www.ncbi.nlm.nih.gov/pubmed/32106551
http://dx.doi.org/10.3390/pharmaceutics12030200