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Topology, Antiviral Functional Residues and Mechanism of IFITM1

Interferon-inducible transmembrane proteins (IFITM1/2/3) have been reported to suppress the entry of a wide range of viruses. However, their antiviral functional residues and specific mechanisms are still unclear. Here, we firstly resolved the topology of IFITM1 on the plasma membrane where N-termin...

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Detalles Bibliográficos
Autores principales: Sun, Fang, Xia, Zhiqiang, Han, Yuewen, Gao, Minjun, Wang, Luyao, Wu, Yingliang, Sabatier, Jean-Marc, Miao, Lixia, Cao, Zhijian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7150853/
https://www.ncbi.nlm.nih.gov/pubmed/32182730
http://dx.doi.org/10.3390/v12030295