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A Novel Model of Cancer Drug Resistance: Oncosomal Release of Cytotoxic and Antibody-Based Drugs

Extracellular vesicles (EVs), such as exosomes or oncosomes, often carry oncogenic molecules derived from tumor cells. In addition, accumulating evidence indicates that tumor cells can eject anti-cancer drugs such as chemotherapeutics and targeted drugs within EVs, a novel mechanism of drug resistan...

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Detalles Bibliográficos
Autores principales: Eguchi, Takanori, Taha, Eman Ahmed, Calderwood, Stuart K., Ono, Kisho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7150871/
https://www.ncbi.nlm.nih.gov/pubmed/32150875
http://dx.doi.org/10.3390/biology9030047