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Porcine Circovirus 2 Induction of ROS Is Responsible for Mitophagy in PK-15 Cells via Activation of Drp1 Phosphorylation

Mitochondrial dynamics is essential for the maintenance of cell homeostasis. Previous studies have shown that porcine circovirus 2 (PCV2) infection decreases the mitochondrial membrane potential and causes the elevation of reactive oxygen species (ROS), which may ultimately lead to mitochondrial apo...

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Detalles Bibliográficos
Autores principales: Zhang, Yikai, Sun, Renjie, Li, Xiaoliang, Fang, Weihuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7150875/
https://www.ncbi.nlm.nih.gov/pubmed/32155766
http://dx.doi.org/10.3390/v12030289