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Quantification and Evaluations of Catechin Hydrate Polymeric Nanoparticles Used in Brain Targeting for the Treatment of Epilepsy

To formulate novel chitosan (CS)-coated–PLGA–nanoparticles (NPs) using a central composite design approach and use them in order to improve brain bioavailability for catechin hydrate (CH) through direct nose-to-central nervous system (CNS) delivery for the evaluation of a comparative biodistribution...

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Detalles Bibliográficos
Autores principales: Ahmad, Niyaz, Ahmad, Rizwan, Alrasheed, Ridha Abdullah, Almatar, Hassan Mohammed Ali, Al-Ramadan, Abdullah Sami, Amir, Mohd, Sarafroz, Md
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7150881/
https://www.ncbi.nlm.nih.gov/pubmed/32120778
http://dx.doi.org/10.3390/pharmaceutics12030203