Spray-Dried Amorphous Solid Dispersions of Griseofulvin in HPC/Soluplus/SDS: Elucidating the Multifaceted Impact of SDS as a Minor Component

This study aimed to elucidate the impact of a common anionic surfactant, sodium dodecyl sulfate (SDS), along with hydroxypropyl cellulose (HPC) and Soluplus (Sol) on the release of griseofulvin (GF), a poorly soluble drug, from amorphous solid dispersions (ASDs). Solutions of 2.5% GF and 2.5%–12.5%...

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Detalles Bibliográficos
Autores principales: Rahman, Mahbubur, Ahmad, Stephanie, Tarabokija, James, Parker, Nathaniel, Bilgili, Ecevit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7150901/
https://www.ncbi.nlm.nih.gov/pubmed/32106495
http://dx.doi.org/10.3390/pharmaceutics12030197

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7150901/
https://www.ncbi.nlm.nih.gov/pubmed/32106495
http://dx.doi.org/10.3390/pharmaceutics12030197

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