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In Silico Optimization of Fiber-Shaped Aerosols in Inhalation Therapy for Augmented Targeting and Deposition across the Respiratory Tract

Motivated by a desire to uncover new opportunities for designing the size and shape of fiber-shaped aerosols towards improved pulmonary drug delivery deposition outcomes, we explore the transport and deposition characteristics of fibers under physiologically inspired inhalation conditions in silico,...

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Detalles Bibliográficos
Autores principales: Shachar-Berman, Lihi, Bhardwaj, Saurabh, Ostrovski, Yan, Das, Prashant, Koullapis, Pantelis, Kassinos, Stavros, Sznitman, Josué
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7150950/
https://www.ncbi.nlm.nih.gov/pubmed/32151016
http://dx.doi.org/10.3390/pharmaceutics12030230