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In Silico Optimization of Fiber-Shaped Aerosols in Inhalation Therapy for Augmented Targeting and Deposition across the Respiratory Tract
Motivated by a desire to uncover new opportunities for designing the size and shape of fiber-shaped aerosols towards improved pulmonary drug delivery deposition outcomes, we explore the transport and deposition characteristics of fibers under physiologically inspired inhalation conditions in silico,...
Autores principales: | Shachar-Berman, Lihi, Bhardwaj, Saurabh, Ostrovski, Yan, Das, Prashant, Koullapis, Pantelis, Kassinos, Stavros, Sznitman, Josué |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7150950/ https://www.ncbi.nlm.nih.gov/pubmed/32151016 http://dx.doi.org/10.3390/pharmaceutics12030230 |
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