Regional Intestinal Drug Permeability and Effects of Permeation Enhancers in Rat

Sufficient colonic absorption is necessary for all systemically acting drugs in dosage forms that release the drug in the large intestine. Preclinically, colonic absorption is often investigated using the rat single-pass intestinal perfusion model. This model can determine intestinal permeability ba...

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Detalles Bibliográficos
Autores principales: Dahlgren, David, Cano-Cebrián, Maria-Jose, Olander, Tobias, Hedeland, Mikael, Sjöblom, Markus, Lennernäs, Hans
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7150977/
https://www.ncbi.nlm.nih.gov/pubmed/32182653
http://dx.doi.org/10.3390/pharmaceutics12030242

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7150977/
https://www.ncbi.nlm.nih.gov/pubmed/32182653
http://dx.doi.org/10.3390/pharmaceutics12030242

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