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In Vitro Performance of an Investigational Vibrating-Membrane Nebulizer with Surfactant under Simulated, Non-Invasive Neonatal Ventilation Conditions: Influence of Continuous Positive Airway Pressure Interface and Nebulizer Positioning on the Lung Dose

Non-invasive delivery of nebulized surfactant has been a long-pursued goal in neonatology. Our aim was to evaluate the performance of an investigational vibrating-membrane nebulizer in a realistic non-invasive neonatal ventilation circuit with different configurations. Surfactant (aerosols were gene...

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Detalles Bibliográficos
Autores principales: Bianco, Federico, Pasini, Elena, Nutini, Marcello, Murgia, Xabier, Stoeckl, Carolin, Schlun, Martin, Hetzer, Uwe, Bonelli, Sauro, Lombardini, Marta, Milesi, Ilaria, Pertile, Marisa, Minocchieri, Stefan, Salomone, Fabrizio, Bucholski, Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7151046/
https://www.ncbi.nlm.nih.gov/pubmed/32178276
http://dx.doi.org/10.3390/pharmaceutics12030257