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Segmental-Dependent Solubility and Permeability as Key Factors Guiding Controlled Release Drug Product Development

The main factors influencing the absorption of orally administered drugs are solubility and permeability, which are location-dependent and may vary along the gastrointestinal tract (GIT). The purpose of this work was to investigate segmental-dependent intestinal absorption and its role in controlled...

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Detalles Bibliográficos
Autores principales: Markovic, Milica, Zur, Moran, Fine-Shamir, Noa, Haimov, Ester, González-Álvarez, Isabel, Dahan, Arik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7151103/
https://www.ncbi.nlm.nih.gov/pubmed/32214015
http://dx.doi.org/10.3390/pharmaceutics12030295