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Segmental-Dependent Solubility and Permeability as Key Factors Guiding Controlled Release Drug Product Development
The main factors influencing the absorption of orally administered drugs are solubility and permeability, which are location-dependent and may vary along the gastrointestinal tract (GIT). The purpose of this work was to investigate segmental-dependent intestinal absorption and its role in controlled...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7151103/ https://www.ncbi.nlm.nih.gov/pubmed/32214015 http://dx.doi.org/10.3390/pharmaceutics12030295 |