On the Usefulness of Two Small-Scale In Vitro Setups in the Evaluation of Luminal Precipitation of Lipophilic Weak Bases in Early Formulation Development

A small-scale biphasic dissolution setup and a small-scale dissolution-permeation (D-P) setup were evaluated for their usefulness in simulating the luminal precipitation of three lipophilic weak bases—dipyridamole, ketoconazole and itraconazole. The transition from the gastric to intestinal environm...

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Detalles Bibliográficos
Autores principales: O’Dwyer, Patrick J., Imanidis, Georgios, Box, Karl J., Reppas, Christos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7151110/
https://www.ncbi.nlm.nih.gov/pubmed/32188116
http://dx.doi.org/10.3390/pharmaceutics12030272

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7151110/
https://www.ncbi.nlm.nih.gov/pubmed/32188116
http://dx.doi.org/10.3390/pharmaceutics12030272

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