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One Single Nucleotide Polymorphism of the TRPM2 Channel Gene Identified as a Risk Factor in Bipolar Disorder Associates With Autism Spectrum Disorder in a Japanese Population

The transient receptor potential melastatin 2 (TRPM2) is a non-specific cation channel, resulting in Ca(2+) influx at warm temperatures from 34 °C to 47 °C, thus including the body temperature range in mammals. TRPM2 channels are activated by β-NAD(+), ADP-ribose (ADPR), cyclic ADPR, and 2′-deoxyade...

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Detalles Bibliográficos
Autores principales: Mahmuda, Naila Al, Yokoyama, Shigeru, Munesue, Toshio, Hayashi, Kenshi, Yagi, Kunimasa, Tsuji, Chiharu, Higashida, Haruhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7151227/
https://www.ncbi.nlm.nih.gov/pubmed/32046066
http://dx.doi.org/10.3390/diseases8010004