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The Comparison of Two Challenging Low Dose APIs in a Continuous Direct Compression Process

Segregation is a common problem in batch-based direct compression (BDC) processes, especially with low-dose tablet products, as is the preparation of a homogenous mixture. The scope of the current work was to explore if a continuous direct compression (CDC) process could serve as a solution for thes...

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Detalles Bibliográficos
Autores principales: Ervasti, Tuomas, Niinikoski, Hannes, Mäki-Lohiluoma, Eero, Leppinen, Heidi, Ketolainen, Jarkko, Korhonen, Ossi, Lakio, Satu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7151305/
https://www.ncbi.nlm.nih.gov/pubmed/32244950
http://dx.doi.org/10.3390/pharmaceutics12030279