Cargando…

Mutational Load and the Functional Fraction of the Human Genome

The fraction of the human genome that is functional is a question of both evolutionary and practical importance. Studies of sequence divergence have suggested that the functional fraction of the human genome is likely to be no more than ∼15%. In contrast, the ENCODE project, a systematic effort to m...

Descripción completa

Detalles Bibliográficos
Autores principales: Galeota-Sprung, Benjamin, Sniegowski, Paul, Ewens, Warren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7151545/
https://www.ncbi.nlm.nih.gov/pubmed/32108234
http://dx.doi.org/10.1093/gbe/evaa040