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Mutational Load and the Functional Fraction of the Human Genome
The fraction of the human genome that is functional is a question of both evolutionary and practical importance. Studies of sequence divergence have suggested that the functional fraction of the human genome is likely to be no more than ∼15%. In contrast, the ENCODE project, a systematic effort to m...
Autores principales: | Galeota-Sprung, Benjamin, Sniegowski, Paul, Ewens, Warren |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7151545/ https://www.ncbi.nlm.nih.gov/pubmed/32108234 http://dx.doi.org/10.1093/gbe/evaa040 |
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