Single Mutation in Hammerhead Ribozyme Favors Cleavage Activity with Manganese over Magnesium

Hammerhead ribozymes are one of the most studied classes of ribozymes so far, from both the structural and biochemical point of views. The activity of most hammerhead ribozymes is cation-dependent. Mg(2+) is one of the most abundant divalent cations in the cell and therefore plays a major role in cl...

Descripción completa

Detalles Bibliográficos
Autores principales: Naghdi, Mohammad Reza, Boutet, Emilie, Mucha, Clarisse, Ouellet, Jonathan, Perreault, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7151607/
https://www.ncbi.nlm.nih.gov/pubmed/32245091
http://dx.doi.org/10.3390/ncrna6010014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7151607/
https://www.ncbi.nlm.nih.gov/pubmed/32245091
http://dx.doi.org/10.3390/ncrna6010014

Ejemplares similares