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Bioisosteric Replacement as a Tool in Anti-HIV Drug Design
Bioisosteric replacement is a powerful tool for modulating the drug-like properties, toxicity, and chemical space of experimental therapeutics. In this review, we focus on selected cases where bioisosteric replacement and scaffold hopping have been used in the development of new anti-HIV-1 therapeut...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7151723/ https://www.ncbi.nlm.nih.gov/pubmed/32121077 http://dx.doi.org/10.3390/ph13030036 |