Quantifying nuclear wide chromatin compaction by phasor analysis of histone Förster resonance energy transfer (FRET) in frequency domain fluorescence lifetime imaging microscopy (FLIM) data

The nanometer spacing between nucleosomes throughout global chromatin organisation modulates local DNA template access, and through continuous dynamic rearrangements, regulates genome function [1]. However, given that nucleosome packaging occurs on a spatial scale well below the diffraction limit, r...

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Detalles Bibliográficos
Autores principales: Liang, Zhen, Lou, Jieqiong, Scipioni, Lorenzo, Gratton, Enrico, Hinde, Elizabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Biochemistry, Genetics and Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7152662/
https://www.ncbi.nlm.nih.gov/pubmed/32300614
http://dx.doi.org/10.1016/j.dib.2020.105401

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7152662/
https://www.ncbi.nlm.nih.gov/pubmed/32300614
http://dx.doi.org/10.1016/j.dib.2020.105401

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