Chronic wasting disease (CWD) prion strains evolve via adaptive diversification of conformers in hosts expressing prion protein polymorphisms

Chronic wasting disease (CWD) is caused by an unknown spectrum of prions and has become enzootic in populations of cervid species that express cellular prion protein (PrP(C)) molecules varying in amino acid composition. These PrP(C) polymorphisms can affect prion transmission, disease progression, n...

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Detalles Bibliográficos
Autores principales: Duque Velásquez, Camilo, Kim, Chae, Haldiman, Tracy, Kim, Chiye, Herbst, Allen, Aiken, Judd, Safar, Jiri G., McKenzie, Debbie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2020
Materias:
Molecular Bases of Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7152757/
https://www.ncbi.nlm.nih.gov/pubmed/32111742
http://dx.doi.org/10.1074/jbc.RA120.012546

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7152757/
https://www.ncbi.nlm.nih.gov/pubmed/32111742
http://dx.doi.org/10.1074/jbc.RA120.012546

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