The green tea polyphenol epigallocatechin-3-gallate (EGCG) restores CDKL5-dependent synaptic defects in vitro and in vivo

CDKL5 deficiency disorder (CDD) is a rare X-linked neurodevelopmental disorder that is characterised by early-onset seizures, intellectual disability, gross motor impairment, and autistic-like features. CDD is caused by mutations in the cyclin-dependent kinase-like 5 (CDKL5) gene that encodes a seri...

Descripción completa

Detalles Bibliográficos
Autores principales: Trovò, L., Fuchs, C., De Rosa, R., Barbiero, I., Tramarin, M., Ciani, E., Rusconi, L., Kilstrup-Nielsen, C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7152796/
https://www.ncbi.nlm.nih.gov/pubmed/32032735
http://dx.doi.org/10.1016/j.nbd.2020.104791

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7152796/
https://www.ncbi.nlm.nih.gov/pubmed/32032735
http://dx.doi.org/10.1016/j.nbd.2020.104791

Ejemplares similares