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FMRP regulates presynaptic localization of neuronal voltage gated calcium channels

Fragile X syndrome (FXS), the most common form of inherited intellectual disability and autism, results from the loss of fragile X mental retardation protein (FMRP). We have recently identified a direct interaction of FMRP with voltage-gated Ca(2+) channels that modulates neurotransmitter release. I...

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Detalles Bibliográficos
Autores principales: Ferron, Laurent, Novazzi, Cesare G., Pilch, Kjara S., Moreno, Cristian, Ramgoolam, Krishma, Dolphin, Annette C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7152798/
https://www.ncbi.nlm.nih.gov/pubmed/31991246
http://dx.doi.org/10.1016/j.nbd.2020.104779