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Development of bone seeker–functionalised microspheres as a targeted local antibiotic delivery system for bone infections

OBJECTIVE: Bone infections are challenging to treat because of limited capability of systemic antibiotics to accumulate at the bone site. To enhance therapeutic action, systemic treatments are commonly combined with local antibiotic-loaded materials. Nevertheless, available drug carriers have undesi...

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Detalles Bibliográficos
Autores principales: Rotman, Stijn G., Thompson, Keith, Grijpma, Dirk W., Richards, Robert G., Moriarty, Thomas F., Eglin, David, Guillaume, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chinese Speaking Orthopaedic Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7152806/
https://www.ncbi.nlm.nih.gov/pubmed/32309139
http://dx.doi.org/10.1016/j.jot.2019.07.006