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Efficacy and safety of methotrexate in the management of inflammatory bowel disease: A systematic review and meta-analysis of randomized, controlled trials

BACKGROUND: The therapeutic role of methotrexate (MTX) for management of inflammatory bowel disease (IBD) remains unclear. METHODS: We systematically reviewed randomized, controlled trials (RCTs) of MTX for induction and maintenance of remission in IBD until January 2020 in accordance with PROSPERO...

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Detalles Bibliográficos
Autores principales: Nielsen, Ole Haagen, Steenholdt, Casper, Juhl, Carsten Bogh, Rogler, Gerhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7152823/
https://www.ncbi.nlm.nih.gov/pubmed/32300735
http://dx.doi.org/10.1016/j.eclinm.2020.100271