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Blocking drug-induced autophagy with chloroquine in HCT-116 colon cancer cells enhances DC maturation and T cell responses induced by tumor cell lysate

Autophagy is an important mechanism for tumor escape, allowing tumor cells to recover from the damage induced by chemotherapy, radiation therapy, and immunotherapy and contributing to the development of resistance. The pharmacological inhibition of autophagy contributes to increase the efficacy of a...

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Detalles Bibliográficos
Autores principales: Zamame Ramirez, Jofer Andree, Romagnoli, Graziela Gorete, Falasco, Bianca Francisco, Gorgulho, Carolina Mendonça, Sanzochi Fogolin, Carla, dos Santos, Daniela Carvalho, Junior, João Pessoa Araújo, Lotze, Michael Thomas, Ureshino, Rodrigo Portes, Kaneno, Ramon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7152898/
https://www.ncbi.nlm.nih.gov/pubmed/32298965
http://dx.doi.org/10.1016/j.intimp.2020.106495