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Blocking drug-induced autophagy with chloroquine in HCT-116 colon cancer cells enhances DC maturation and T cell responses induced by tumor cell lysate
Autophagy is an important mechanism for tumor escape, allowing tumor cells to recover from the damage induced by chemotherapy, radiation therapy, and immunotherapy and contributing to the development of resistance. The pharmacological inhibition of autophagy contributes to increase the efficacy of a...
Autores principales: | Zamame Ramirez, Jofer Andree, Romagnoli, Graziela Gorete, Falasco, Bianca Francisco, Gorgulho, Carolina Mendonça, Sanzochi Fogolin, Carla, dos Santos, Daniela Carvalho, Junior, João Pessoa Araújo, Lotze, Michael Thomas, Ureshino, Rodrigo Portes, Kaneno, Ramon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier B.V.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7152898/ https://www.ncbi.nlm.nih.gov/pubmed/32298965 http://dx.doi.org/10.1016/j.intimp.2020.106495 |
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