Pharmacokinetic Comparisons of Naringenin and Naringenin-Nicotinamide Cocrystal in Rats by LC-MS/MS

Naringenin (NAR), 4′,5,7-trihydroxydihydroflavone, has a wide range of pharmacological activities but shows poor water solubility and low bioavailability. The pharmacokinetics and bioavailability of naringenin-nicotinamide cocrystal (NAR-NCT), which offers improved solubility, were evaluated in this...

Descripción completa

Detalles Bibliográficos
Autores principales: Xu, Dan, Zhang, Gui-Qiu, Zhang, Ting-Ting, Jin, Bo, Ma, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7152953/
https://www.ncbi.nlm.nih.gov/pubmed/32322425
http://dx.doi.org/10.1155/2020/8364218

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7152953/
https://www.ncbi.nlm.nih.gov/pubmed/32322425
http://dx.doi.org/10.1155/2020/8364218

Ejemplares similares