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Pharmacokinetic Comparisons of Naringenin and Naringenin-Nicotinamide Cocrystal in Rats by LC-MS/MS
Naringenin (NAR), 4′,5,7-trihydroxydihydroflavone, has a wide range of pharmacological activities but shows poor water solubility and low bioavailability. The pharmacokinetics and bioavailability of naringenin-nicotinamide cocrystal (NAR-NCT), which offers improved solubility, were evaluated in this...
Autores principales: | Xu, Dan, Zhang, Gui-Qiu, Zhang, Ting-Ting, Jin, Bo, Ma, Chen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7152953/ https://www.ncbi.nlm.nih.gov/pubmed/32322425 http://dx.doi.org/10.1155/2020/8364218 |
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