Pharmacologic inhibition of RGD‐binding integrins ameliorates fibrosis and improves function following kidney injury

Fibrosis is a final common pathway for many causes of progressive chronic kidney disease (CKD). Arginine–glycine–aspartic acid (RGD)‐binding integrins are important mediators of the pro‐fibrotic response by activating latent TGF‐β at sites of injury and by providing myofibroblasts information about...

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Detalles Bibliográficos
Autores principales: Basta, Jeannine, Robbins, Lynn, Stout, Lisa, Prinsen, Michael J., Griggs, David W., Rauchman, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7153038/
https://www.ncbi.nlm.nih.gov/pubmed/32281744
http://dx.doi.org/10.14814/phy2.14329

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7153038/
https://www.ncbi.nlm.nih.gov/pubmed/32281744
http://dx.doi.org/10.14814/phy2.14329

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