Determining a Bayesian predictive power stopping rule for futility in a non-inferiority trial with binary outcomes

BACKGROUND/AIMS: Non-inferiority trials investigate whether a novel intervention, which typically has other benefits (i.e., cheaper or safer), has similar clinical effectiveness to currently available treatments. In situations where interim evidence in a non-inferiority trial suggests that the novel...

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Detalles Bibliográficos
Autores principales: Heath, Anna, Offringa, Martin, Pechlivanoglou, Petros, Rios, Juan David, Klassen, Terry P., Poonai, Naveen, Pullenayegum, Eleanor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7153169/
https://www.ncbi.nlm.nih.gov/pubmed/32300671
http://dx.doi.org/10.1016/j.conctc.2020.100561

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7153169/
https://www.ncbi.nlm.nih.gov/pubmed/32300671
http://dx.doi.org/10.1016/j.conctc.2020.100561

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