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Determining a Bayesian predictive power stopping rule for futility in a non-inferiority trial with binary outcomes
BACKGROUND/AIMS: Non-inferiority trials investigate whether a novel intervention, which typically has other benefits (i.e., cheaper or safer), has similar clinical effectiveness to currently available treatments. In situations where interim evidence in a non-inferiority trial suggests that the novel...
Autores principales: | Heath, Anna, Offringa, Martin, Pechlivanoglou, Petros, Rios, Juan David, Klassen, Terry P., Poonai, Naveen, Pullenayegum, Eleanor |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7153169/ https://www.ncbi.nlm.nih.gov/pubmed/32300671 http://dx.doi.org/10.1016/j.conctc.2020.100561 |
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