Dual role of the L-arginine–ADMA–NO pathway in systemic hypoxic vasodilation and pulmonary hypoxic vasoconstriction

In healthy vascular endothelium, nitric oxide acts as a vasodilator paracrine mediator on adjacent smooth muscle cells. By activating soluble guanylyl cyclase, nitric oxide stimulates cyclic guanosine monophosphate (cGMP) which causes relaxation of vascular smooth muscle (vasodilation) and inhibitio...

Descripción completa

Detalles Bibliográficos
Autores principales: Böger, Rainer, Hannemann, Juliane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Special Issue for the 1st international DECIPHER Symposium on Hypoxia and the Lung
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7153195/
https://www.ncbi.nlm.nih.gov/pubmed/32313645
http://dx.doi.org/10.1177/2045894020918850

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7153195/
https://www.ncbi.nlm.nih.gov/pubmed/32313645
http://dx.doi.org/10.1177/2045894020918850

Ejemplares similares