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Assessment of the Mode of Action Underlying the Effects of GenX in Mouse Liver and Implications for Assessing Human Health Risks

GenX is an alternative to environmentally persistent long-chain perfluoroalkyl and polyfluoroalkyl substances. Mice exposed to GenX exhibit liver hypertrophy, elevated peroxisomal enzyme activity, and other apical endpoints consistent with peroxisome proliferators. To investigate the potential role...

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Detalles Bibliográficos
Autores principales: Chappell, Grace A., Thompson, Chad M., Wolf, Jeffrey C., Cullen, John M., Klaunig, James E., Haws, Laurie C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7153225/
https://www.ncbi.nlm.nih.gov/pubmed/32138627
http://dx.doi.org/10.1177/0192623320905803