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Assessment of the Mode of Action Underlying the Effects of GenX in Mouse Liver and Implications for Assessing Human Health Risks
GenX is an alternative to environmentally persistent long-chain perfluoroalkyl and polyfluoroalkyl substances. Mice exposed to GenX exhibit liver hypertrophy, elevated peroxisomal enzyme activity, and other apical endpoints consistent with peroxisome proliferators. To investigate the potential role...
Autores principales: | Chappell, Grace A., Thompson, Chad M., Wolf, Jeffrey C., Cullen, John M., Klaunig, James E., Haws, Laurie C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7153225/ https://www.ncbi.nlm.nih.gov/pubmed/32138627 http://dx.doi.org/10.1177/0192623320905803 |
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