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PAC proton-activated chloride channel contributes to acid-induced cell death in primary rat cortical neurons

Severe local acidosis causes tissue damage and pain, and is associated with many diseases, including cerebral and cardiac ischemia, cancer, infection, and inflammation. However, the molecular mechanisms of the cellular response to extracellular acidic environment are not fully understood. We recentl...

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Detalles Bibliográficos
Autores principales: Osei-Owusu, James, Yang, Junhua, Del Carmen Vitery, Maria, Tian, Mengnan, Qiu, Zhaozhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7153786/
https://www.ncbi.nlm.nih.gov/pubmed/32093550
http://dx.doi.org/10.1080/19336950.2020.1730019