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PAC proton-activated chloride channel contributes to acid-induced cell death in primary rat cortical neurons
Severe local acidosis causes tissue damage and pain, and is associated with many diseases, including cerebral and cardiac ischemia, cancer, infection, and inflammation. However, the molecular mechanisms of the cellular response to extracellular acidic environment are not fully understood. We recentl...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7153786/ https://www.ncbi.nlm.nih.gov/pubmed/32093550 http://dx.doi.org/10.1080/19336950.2020.1730019 |