Deciphering the transcriptomic landscape of tumor-infiltrating CD8 lymphocytes in B16 melanoma tumors with single-cell RNA-Seq

Recent studies have proposed that tumor-specific tumor-infiltrating CD8(+) T lymphocytes (CD8 TIL) can be classified into two main groups: “exhausted” TILs, characterized by high expression of the inhibitory receptors PD-1 and TIM-3 and lack of transcription factor 1 (Tcf1); and “memory-like” TILs,...

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Detalles Bibliográficos
Autores principales: Carmona, Santiago J., Siddiqui, Imran, Bilous, Mariia, Held, Werner, Gfeller, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7153840/
https://www.ncbi.nlm.nih.gov/pubmed/32313720
http://dx.doi.org/10.1080/2162402X.2020.1737369

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7153840/
https://www.ncbi.nlm.nih.gov/pubmed/32313720
http://dx.doi.org/10.1080/2162402X.2020.1737369

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