Cargando…

GLP-1 Notch—LAG-1 CSL control of the germline stem cell fate is mediated by transcriptional targets lst-1 and sygl-1

Stem cell systems are essential for the development and maintenance of polarized tissues. Intercellular signaling pathways control stem cell systems, where niche cells signal stem cells to maintain the stem cell fate/self-renewal and inhibit differentiation. In the C. elegans germline, GLP-1 Notch s...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Jian, Mohammad, Ariz, Pazdernik, Nanette, Huang, Huiyan, Bowman, Beth, Tycksen, Eric, Schedl, Tim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7153901/
https://www.ncbi.nlm.nih.gov/pubmed/32196486
http://dx.doi.org/10.1371/journal.pgen.1008650