The nanophthalmos protein TMEM98 inhibits MYRF self-cleavage and is required for eye size specification

The precise control of eye size is essential for normal vision. TMEM98 is a highly conserved and widely expressed gene which appears to be involved in eye size regulation. Mutations in human TMEM98 are found in patients with nanophthalmos (very small eyes) and variants near the gene are associated i...

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Detalles Bibliográficos
Autores principales: Cross, Sally H., Mckie, Lisa, Hurd, Toby W., Riley, Sam, Wills, Jimi, Barnard, Alun R., Young, Fiona, MacLaren, Robert E., Jackson, Ian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7153906/
https://www.ncbi.nlm.nih.gov/pubmed/32236127
http://dx.doi.org/10.1371/journal.pgen.1008583

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7153906/
https://www.ncbi.nlm.nih.gov/pubmed/32236127
http://dx.doi.org/10.1371/journal.pgen.1008583

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